The fraction excreted unchanged helps assess the potential effect of renal and hepatic diseases on drug elimination 原型排泄分数有助于评估肾病或肝病对药物消除的潜在影响。
2.
A low fraction indicates that hepatic metabolism is the likely mechanism of elimination and that hepatic disease may therefore affect drug elimination 低分数表明肝脏代谢很可能是药物的消除机制,因而,肝脏疾病可以影响药物的消除。